Intrinsic transcriptional heterogeneity in neuroblastoma guides mechanistic and therapeutic insights

Cell state is controlled by master transcription factors (mTFs) that determine the cellular gene expression program. Cancer cells acquire dysregulated gene expression programs by mutational and non-mutational processes. Intratumoral heterogeneity can result from cells displaying distinct mTF-regulat...

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Detalles Bibliográficos
Autores principales: Shendy, Noha A.M., Zimmerman, Mark W., Abraham, Brian J., Durbin, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133465/
https://www.ncbi.nlm.nih.gov/pubmed/35584622
http://dx.doi.org/10.1016/j.xcrm.2022.100632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133465/
https://www.ncbi.nlm.nih.gov/pubmed/35584622
http://dx.doi.org/10.1016/j.xcrm.2022.100632

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