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Intrinsic transcriptional heterogeneity in neuroblastoma guides mechanistic and therapeutic insights
Cell state is controlled by master transcription factors (mTFs) that determine the cellular gene expression program. Cancer cells acquire dysregulated gene expression programs by mutational and non-mutational processes. Intratumoral heterogeneity can result from cells displaying distinct mTF-regulat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133465/ https://www.ncbi.nlm.nih.gov/pubmed/35584622 http://dx.doi.org/10.1016/j.xcrm.2022.100632 |