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Development of Novel CD47-Specific ADCs Possessing High Potency Against Non-Small Cell Lung Cancer in vitro and in vivo

Targeted therapies hold promise for efficiently and accurately delivering cytotoxic drugs directly to tumor tissue to exert anticancer effects. CD47 is a membrane protein expressed in a variety of malignant tumors and hematopoietic cells, which plays a key role in immune escape and tumor progression...

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Detalles Bibliográficos
Autores principales: Chiang, Zu-Chian, Fang, Shubin, Shen, Yang-kun, Cui, Dongya, Weng, Huanjiao, Wang, Dawei, Zhao, Yuxiang, Lin, Jizhen, Chen, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133542/
https://www.ncbi.nlm.nih.gov/pubmed/35646646
http://dx.doi.org/10.3389/fonc.2022.857927