Short cytoplasmic isoform of IL1R1/CD121a mediates IL1β induced proliferation of synovium-derived mesenchymal stem/stromal cells through ERK1/2 pathway

OBJECTIVES: IL1β enhances proliferation of synovial mesenchymal stem/stromal cells (synMSCs) although they don't express its receptor, IL1R1/CD121a, on the cell surface. This study was aimed to elucidate the underlying mechanisms of IL1β-mediated growth promotion. METHODS: Human synMSCs were is...

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Detalles Bibliográficos
Autores principales: Tang, Guo, Asou, Yoshinori, Matsumura, Etsuko, Nakagawa, Yusuke, Miyatake, Kazumasa, Katagiri, Hiroki, Nakamura, Tomomasa, Koga, Hideyuki, Komori, Keiichiro, Sekiya, Ichiro, Ezura, Yoich, Tsuji, Kunikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133583/
https://www.ncbi.nlm.nih.gov/pubmed/35647352
http://dx.doi.org/10.1016/j.heliyon.2022.e09476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133583/
https://www.ncbi.nlm.nih.gov/pubmed/35647352
http://dx.doi.org/10.1016/j.heliyon.2022.e09476

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