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Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia
Activated microglia release extracellular vesicles (EVs) as modulators of brain homeostasis and innate immunity. However, the molecules critical for regulating EV production from microglia are poorly understood. Here we establish a murine microglial cell model to monitor EV secretion by measuring th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133589/ https://www.ncbi.nlm.nih.gov/pubmed/35545052 http://dx.doi.org/10.1016/j.celrep.2022.110791 |