Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia

Activated microglia release extracellular vesicles (EVs) as modulators of brain homeostasis and innate immunity. However, the molecules critical for regulating EV production from microglia are poorly understood. Here we establish a murine microglial cell model to monitor EV secretion by measuring th...

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Detalles Bibliográficos
Autores principales: Ruan, Zhi, Takamatsu-Yukawa, Kayo, Wang, Yuzhi, Ushman, Margaret L., Labadorf, Adam Thomas, Ericsson, Maria, Ikezu, Seiko, Ikezu, Tsuneya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133589/
https://www.ncbi.nlm.nih.gov/pubmed/35545052
http://dx.doi.org/10.1016/j.celrep.2022.110791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133589/
https://www.ncbi.nlm.nih.gov/pubmed/35545052
http://dx.doi.org/10.1016/j.celrep.2022.110791

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