Soluble SIRP-Alpha Promotes Murine Acute Lung Injury Through Suppressing Macrophage Phagocytosis

Soluble signal regulatory protein-alpha (SIRP-alpha) is elevated in bronchoalveolar lavage (BAL) of mice with lipopolysaccharides (LPS)-induced acute lung injury (ALI). To define the role of soluble SIRP-alpha in the pathogenesis of ALI, we established murine ALI in wild-type (WT) and SIRP-alpha kno...

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Detalles Bibliográficos
Autores principales: Shen, Qinjun, Zhao, Li, Pan, Linyue, Li, Dandan, Chen, Gang, Chen, Zhihong, Jiang, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133620/
https://www.ncbi.nlm.nih.gov/pubmed/35634325
http://dx.doi.org/10.3389/fimmu.2022.865579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133620/
https://www.ncbi.nlm.nih.gov/pubmed/35634325
http://dx.doi.org/10.3389/fimmu.2022.865579

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