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Soluble SIRP-Alpha Promotes Murine Acute Lung Injury Through Suppressing Macrophage Phagocytosis
Soluble signal regulatory protein-alpha (SIRP-alpha) is elevated in bronchoalveolar lavage (BAL) of mice with lipopolysaccharides (LPS)-induced acute lung injury (ALI). To define the role of soluble SIRP-alpha in the pathogenesis of ALI, we established murine ALI in wild-type (WT) and SIRP-alpha kno...
Autores principales: | Shen, Qinjun, Zhao, Li, Pan, Linyue, Li, Dandan, Chen, Gang, Chen, Zhihong, Jiang, Zhilong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133620/ https://www.ncbi.nlm.nih.gov/pubmed/35634325 http://dx.doi.org/10.3389/fimmu.2022.865579 |
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