E3 ligase HUWE1 promotes PDGF D-mediated osteoblastic differentiation of mesenchymal stem cells by effecting polyubiquitination of β-PDGFR

Mesenchymal stem cells (MSCs) are adult stem cell populations and exhibit great potential in regenerative medicine and oncology. Platelet-derived growth factors (PDGFs) are well known to regulate MSC biology through their chemotactic and mitogenic properties. However, their direct roles in the regul...

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Detalles Bibliográficos
Autores principales: Pham, Tri, Najy, Abdo J., Kim, Hyeong-Reh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133640/
https://www.ncbi.nlm.nih.gov/pubmed/35472332
http://dx.doi.org/10.1016/j.jbc.2022.101981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133640/
https://www.ncbi.nlm.nih.gov/pubmed/35472332
http://dx.doi.org/10.1016/j.jbc.2022.101981

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