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The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection

The signaling pathways and cellular functions regulated by the four Numb-associated kinases are largely unknown. We reported that AAK1 and GAK control intracellular trafficking of RNA viruses and revealed a requirement for BIKE in early and late stages of dengue virus (DENV) infection. However, the...

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Detalles Bibliográficos
Autores principales: Schor, Stanford, Pu, Szuyuan, Nicolaescu, Vlad, Azari, Siavash, Kõivomägi, Mardo, Karim, Marwah, Cassonnet, Patricia, Saul, Sirle, Neveu, Gregory, Yueh, Andrew, Demeret, Caroline, Skotheim, Jan M., Jacob, Yves, Randall, Glenn, Einav, Shirit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133654/
https://www.ncbi.nlm.nih.gov/pubmed/35452674
http://dx.doi.org/10.1016/j.jbc.2022.101956