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miR-15a and miR-15b modulate natural killer and CD8(+)T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma

Neuroblastoma (NB) is an enigmatic and deadliest pediatric cancer to treat. The major obstacles to the effective immunotherapy treatments in NB are defective immune cells and the immune evasion tactics deployed by the tumor cells and the stromal microenvironment. Nervous system development during em...

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Detalles Bibliográficos
Autores principales: Pathania, Anup S., Prathipati, Philip, Olwenyi, Omalla A., Chava, Srinivas, Smith, Oghenetejiri V., Gupta, Subash C., Chaturvedi, Nagendra K., Byrareddy, Siddappa N., Coulter, Don W., Challagundla, Kishore B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133764/
https://www.ncbi.nlm.nih.gov/pubmed/35663229
http://dx.doi.org/10.1016/j.omto.2022.03.010