Development of a mitochondrial sirtuin 4 FRET assay based on its activity for removing 3-hydroxy-3-methylglutaryl (HMG) modification

SIRT4 belongs to one of three mitochondrial sirtuins, which plays important roles in regulating many biological processes and has significant implications for treating several human diseases. However, the development of those small compounds that can modulate SIRT4 activities is limited because ther...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhao, Yonglong, Cao, Zhuoxian, Wang, Jie, Liu, Ting, Li, Yongjun, Wang, Yuanyuan, He, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133976/
https://www.ncbi.nlm.nih.gov/pubmed/35747080
http://dx.doi.org/10.1039/d0ra09424b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133976/
https://www.ncbi.nlm.nih.gov/pubmed/35747080
http://dx.doi.org/10.1039/d0ra09424b

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