Monitoring haemodynamic changes in rodent models to better inform safety pharmacology: Novel insights from in vivo studies and waveform analysis

Animal models are essential for assessing cardiovascular responses to novel therapeutics. Cardiovascular safety liabilities represent a leading cause of drug attrition and better preclinical measurements are essential to predict drug-related toxicities. Presently, radiotelemetric approaches recordin...

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Detalles Bibliográficos
Autores principales: Van Daele, Marieke, Cooper, Samantha L, Pannucci, Patrizia, Wragg, Edward S, March, Julie, de Jong, Iwan, Woolard, Jeanette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Applications of waveform analysis in cardiovascular disease- Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133998/
https://www.ncbi.nlm.nih.gov/pubmed/35646334
http://dx.doi.org/10.1177/20480040221092893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133998/
https://www.ncbi.nlm.nih.gov/pubmed/35646334
http://dx.doi.org/10.1177/20480040221092893

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