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Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma

Immunotherapy has improved the treatment of malignant skin cancer of the melanoma type, yet overall clinical response rates remain low. Combination therapies could be key to meet this cogent medical need. Because epigenetic hallmarks represent promising combination therapy targets, we studied the im...

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Detalles Bibliográficos
Autores principales: De Beck, Lien, Awad, Robin Maximilian, Basso, Veronica, Casares, Noelia, De Ridder, Kirsten, De Vlaeminck, Yannick, Gnata, Alessandra, Goyvaerts, Cleo, Lecocq, Quentin, San José-Enériz, Edurne, Verhulst, Stefaan, Maes, Ken, Vanderkerken, Karin, Agirre, Xabier, Prosper, Felipe, Lasarte, Juan José, Mondino, Anna, Breckpot, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134079/
https://www.ncbi.nlm.nih.gov/pubmed/35634329
http://dx.doi.org/10.3389/fimmu.2022.799636