Pemphigus Foliaceus Autoantibodies Induce Redistribution Primarily of Extradesmosomal Desmoglein 1 in the Cell Membrane

The autoimmune dermatosis pemphigus foliaceus (PF) is predominantly caused by IgG autoantibodies against the desmosomal cadherin desmoglein (Dsg) 1. The exact mechanisms that lead to the characteristic epidermal blistering are not yet fully understood. In the present study, we used a variety of biop...

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Detalles Bibliográficos
Autores principales: Hiermaier, Matthias, Kugelmann, Daniela, Radeva, Mariya Y., Didona, Dario, Ghoreschi, Kamran, Farzan, Solimani, Hertl, Michael, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134081/
https://www.ncbi.nlm.nih.gov/pubmed/35634274
http://dx.doi.org/10.3389/fimmu.2022.882116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134081/
https://www.ncbi.nlm.nih.gov/pubmed/35634274
http://dx.doi.org/10.3389/fimmu.2022.882116

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