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Pemphigus Foliaceus Autoantibodies Induce Redistribution Primarily of Extradesmosomal Desmoglein 1 in the Cell Membrane
The autoimmune dermatosis pemphigus foliaceus (PF) is predominantly caused by IgG autoantibodies against the desmosomal cadherin desmoglein (Dsg) 1. The exact mechanisms that lead to the characteristic epidermal blistering are not yet fully understood. In the present study, we used a variety of biop...
Autores principales: | Hiermaier, Matthias, Kugelmann, Daniela, Radeva, Mariya Y., Didona, Dario, Ghoreschi, Kamran, Farzan, Solimani, Hertl, Michael, Waschke, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134081/ https://www.ncbi.nlm.nih.gov/pubmed/35634274 http://dx.doi.org/10.3389/fimmu.2022.882116 |
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