Loss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking

Systemic lupus erythematosus (SLE) is a complex, heterogeneous autoimmune disease. A common manifestation, lupus nephritis, arises from immune complex deposition in the kidney microvasculature promoting leukocyte activation and infiltration, which triggers glomerular damage and renal dysfunction. CD...

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Detalles Bibliográficos
Autores principales: Gottschalk, Timothy A., Hall, Pamela, Tsantikos, Evelyn, L’Estrange-Stranieri, Elan, Hickey, Michael J., Hibbs, Margaret L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134083/
https://www.ncbi.nlm.nih.gov/pubmed/35634296
http://dx.doi.org/10.3389/fimmu.2022.875359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134083/
https://www.ncbi.nlm.nih.gov/pubmed/35634296
http://dx.doi.org/10.3389/fimmu.2022.875359

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