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Loss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking
Systemic lupus erythematosus (SLE) is a complex, heterogeneous autoimmune disease. A common manifestation, lupus nephritis, arises from immune complex deposition in the kidney microvasculature promoting leukocyte activation and infiltration, which triggers glomerular damage and renal dysfunction. CD...
Autores principales: | Gottschalk, Timothy A., Hall, Pamela, Tsantikos, Evelyn, L’Estrange-Stranieri, Elan, Hickey, Michael J., Hibbs, Margaret L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134083/ https://www.ncbi.nlm.nih.gov/pubmed/35634296 http://dx.doi.org/10.3389/fimmu.2022.875359 |
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