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microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

MicroRNAs (miRNAs/miRs) have aroused increasing attention in colorectal cancer (CRC) therapy. This study is designed for a detailed analysis of the roles of miR-16-5p and forkhead box K1 (FOXK1) in cell angiogenesis and proliferation during CRC in addition to their underlying mechanisms. CRC tissues...

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Detalles Bibliográficos
Autores principales: Huang, Xin, Xu, Xuan, Ke, Huajing, Pan, Xiaolin, Ai, Jiaoyu, Xie, Ruyi, Lan, Guilian, Hu, Yang, Wu, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134092/
https://www.ncbi.nlm.nih.gov/pubmed/35536149
http://dx.doi.org/10.4081/ejh.2022.3333