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Characterization and Sequence Mapping of Large RNA and mRNA Therapeutics Using Mass Spectrometry
[Image: see text] Large RNA including mRNA (mRNA) has emerged as an important new class of therapeutics. Recently, this has been demonstrated by two highly efficacious vaccines based on mRNA sequences encoding for a modified version of the SARS-CoV-2 spike protein. There is currently significant dem...
Autores principales: | Vanhinsbergh, Christina J., Criscuolo, Angela, Sutton, Jennifer N., Murphy, Keeley, Williamson, Andrew J. K., Cook, Ken, Dickman, Mark J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134182/ https://www.ncbi.nlm.nih.gov/pubmed/35549087 http://dx.doi.org/10.1021/acs.analchem.2c00765 |
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