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Systematic Development of Solid Lipid Nanoparticles of Abiraterone Acetate with Improved Oral Bioavailability and Anticancer Activity for Prostate Carcinoma Treatment

[Image: see text] In the present work, an attempt was undertaken to improve the oral bioavailability and anticancer activity of abiraterone acetate. Solid lipid nanoparticles (SLNs) were developed using the quality by design (QbD) principles and evaluated through in vitro, ex vivo, and in vivo studi...

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Detalles Bibliográficos
Autores principales: Beg, Sarwar, Malik, Ankit K., Ansari, Mohammad Javed, Malik, Asrar A., Ali, Ahmed Mahmoud Abdelhaleem, Theyab, Abdulrahman, Algahtani, Mohammad, Almalki, Waleed H., Alharbi, Khalid S., Alenezi, Sattam K., Barkat, Md. Abul, Rahman, Mahfoozur, Choudhry, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134222/
https://www.ncbi.nlm.nih.gov/pubmed/35647451
http://dx.doi.org/10.1021/acsomega.1c07254