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Systematic Development of Solid Lipid Nanoparticles of Abiraterone Acetate with Improved Oral Bioavailability and Anticancer Activity for Prostate Carcinoma Treatment
[Image: see text] In the present work, an attempt was undertaken to improve the oral bioavailability and anticancer activity of abiraterone acetate. Solid lipid nanoparticles (SLNs) were developed using the quality by design (QbD) principles and evaluated through in vitro, ex vivo, and in vivo studi...
Autores principales: | Beg, Sarwar, Malik, Ankit K., Ansari, Mohammad Javed, Malik, Asrar A., Ali, Ahmed Mahmoud Abdelhaleem, Theyab, Abdulrahman, Algahtani, Mohammad, Almalki, Waleed H., Alharbi, Khalid S., Alenezi, Sattam K., Barkat, Md. Abul, Rahman, Mahfoozur, Choudhry, Hani |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134222/ https://www.ncbi.nlm.nih.gov/pubmed/35647451 http://dx.doi.org/10.1021/acsomega.1c07254 |
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