Oxygen Desaturation Is Associated With Fibrocyte Activation via Epidermal Growth Factor Receptor/Hypoxia-Inducible Factor-1α Axis in Chronic Obstructive Pulmonary Disease

Fibrocytes are bloodborne mesenchymal progenitors which accumulate and differentiate at the disease site. We investigated whether hypoxemia activates fibrocytes, accelerating airflow limitation and exercise intolerance in chronic obstructive pulmonary disease (COPD) patients. Flow cytometry was used...

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Detalles Bibliográficos
Autores principales: Wang, Chun-Hua, Lo, Chun-Yu, Huang, Hung-Yu, Wang, Tsai-Yu, Weng, Chih-Ming, Chen, Chih-Jung, Huang, Yu-Chen, Chung, Fu-Tsai, Lin, Chang-Wei, Chung, Kian Fan, Kuo, Han-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134242/
https://www.ncbi.nlm.nih.gov/pubmed/35634326
http://dx.doi.org/10.3389/fimmu.2022.852713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134242/
https://www.ncbi.nlm.nih.gov/pubmed/35634326
http://dx.doi.org/10.3389/fimmu.2022.852713

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