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Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis

COVID-19 is characterized by hyperactivation by inflammatory cytokines and recruitment of macrophages, neutrophils, and other immune cells, all hallmarks of a strong inflammatory response that can lead to severe complications and multi-organ damage. Mortality in COVID-19 patients is associated with...

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Detalles Bibliográficos
Autores principales: Aloul, Karim M., Nielsen, Josefine Eilsø, Defensor, Erwin B., Lin, Jennifer S., Fortkort, John A., Shamloo, Mehrdad, Cirillo, Jeffrey D., Gombart, Adrian F., Barron, Annelise E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134243/
https://www.ncbi.nlm.nih.gov/pubmed/35634307
http://dx.doi.org/10.3389/fimmu.2022.880961