A New Pathway for the Preparation of Pyrano[2,3-c]pyrazoles and molecular Docking as Inhibitors of p38 MAP Kinase

[Image: see text] We report a new pathway to synthesize pyrano[2,3-c]pyrazoles and their binding mode to p38 MAP kinase. Pyrano[2,3-c]pyrazole derivatives have been prepared through a four-component reaction of benzyl alcohols, ethyl acetoacetate, phenylhydrazine, and malononitrile in the presence o...

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Detalles Bibliográficos
Autores principales: Nguyen, Hai Truong, Truong, Minh-Nhat Ha, Le, Tan Van, Vo, Nam Tri, Nguyen, Hoang Duc, Tran, Phuong Hoang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134431/
https://www.ncbi.nlm.nih.gov/pubmed/35647469
http://dx.doi.org/10.1021/acsomega.2c01814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134431/
https://www.ncbi.nlm.nih.gov/pubmed/35647469
http://dx.doi.org/10.1021/acsomega.2c01814

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