β-Barrel Nanopores with an Acidic–Aromatic Sensing Region Identify Proteinogenic Peptides at Low pH

[Image: see text] Biological nanopores are emerging as sensitive single-molecule sensors for proteins and peptides. The heterogeneous charge of a polypeptide chain, however, can complicate or prevent the capture and translocation of peptides and unfolded proteins across nanopores. Here, we show that...

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Detalles Bibliográficos
Autores principales: Versloot, Roderick Corstiaan Abraham, Straathof, Sabine Angenieta Paulina, Stouwie, Gemma, Tadema, Matthijs Jonathan, Maglia, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134492/
https://www.ncbi.nlm.nih.gov/pubmed/35302739
http://dx.doi.org/10.1021/acsnano.1c11455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134492/
https://www.ncbi.nlm.nih.gov/pubmed/35302739
http://dx.doi.org/10.1021/acsnano.1c11455

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