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Upregulation of TGF-β-induced HSP27 by HSP90 inhibitors in osteoblasts
BACKGROUND: Heat shock protein (HSP) 90 functions as a molecular chaperone and is constitutively expressed and induced in response to stress in many cell types. We have previously demonstrated that transforming growth factor-β (TGF-β), the most abundant cytokine in bone cells, induces the expression...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134601/ https://www.ncbi.nlm.nih.gov/pubmed/35619094 http://dx.doi.org/10.1186/s12891-022-05419-1 |