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Upregulation of TGF-β-induced HSP27 by HSP90 inhibitors in osteoblasts

BACKGROUND: Heat shock protein (HSP) 90 functions as a molecular chaperone and is constitutively expressed and induced in response to stress in many cell types. We have previously demonstrated that transforming growth factor-β (TGF-β), the most abundant cytokine in bone cells, induces the expression...

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Detalles Bibliográficos
Autores principales: Kuroyanagi, Gen, Tokuda, Haruhiko, Fujita, Kazuhiko, Kawabata, Tetsu, Sakai, Go, Kim, Woo, Hioki, Tomoyuki, Tachi, Junko, Matsushima-Nishiwaki, Rie, Otsuka, Takanobu, Iida, Hiroki, Kozawa, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134601/
https://www.ncbi.nlm.nih.gov/pubmed/35619094
http://dx.doi.org/10.1186/s12891-022-05419-1