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Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs
BACKGROUND: Gene regulation is critical for proper cellular function. Next-generation sequencing technology has revealed the presence of regulatory networks that regulate gene expression and essential cellular functions. Studies investigating the epigenome have begun to uncover the complex mechanism...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134605/ https://www.ncbi.nlm.nih.gov/pubmed/35614386 http://dx.doi.org/10.1186/s12864-022-08637-y |