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Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs

BACKGROUND: Gene regulation is critical for proper cellular function. Next-generation sequencing technology has revealed the presence of regulatory networks that regulate gene expression and essential cellular functions. Studies investigating the epigenome have begun to uncover the complex mechanism...

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Detalles Bibliográficos
Autores principales:	Merrill, Collin B., Montgomery, Austin B., Pabon, Miguel A., Shabalin, Andrey A., Rodan, Aylin R., Rothenfluh, Adrian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134605/ https://www.ncbi.nlm.nih.gov/pubmed/35614386 http://dx.doi.org/10.1186/s12864-022-08637-y

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