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BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c-Fos/NFATc1
BACKGROUND: Dysregulated osteoclast activity due to altered osteoclast differentiation causes multiple bone diseases. Osteoclasts are multinucleated giant cells derived from hematopoietic stem cells and play a major role in bone absorption. However, the mechanisms underlying the tight regulation of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134610/ https://www.ncbi.nlm.nih.gov/pubmed/35619122 http://dx.doi.org/10.1186/s13578-022-00813-7 |