Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet

BACKGROUND: Hepatocyte nuclear factor 4α (HNF4α) and glucocorticoid receptor (GR), master regulators of liver metabolism, are down-regulated in fatty liver diseases. The present study aimed to elucidate the role of down-regulation of HNF4α and GR in fatty liver and hyperlipidemia. METHODS: Adult mic...

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Detalles Bibliográficos
Autores principales: Lu, Hong, Lei, Xiaohong, Winkler, Rebecca, John, Savio, Kumar, Devendra, Li, Wenkuan, Alnouti, Yazen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134643/
https://www.ncbi.nlm.nih.gov/pubmed/35614477
http://dx.doi.org/10.1186/s12944-022-01654-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134643/
https://www.ncbi.nlm.nih.gov/pubmed/35614477
http://dx.doi.org/10.1186/s12944-022-01654-6

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