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Evolving strategy for an evolving virus: Development of real-time PCR assays for detecting all SARS-CoV-2 variants of concern

In order to detect the SARS-CoV-2 variants of concern (VOCs), five real-time reverse transcriptase PCR (rRT-PCR) assays were designed to target the critical discriminatory mutations responsible for the following amino acid changes in the spike protein: two Δ69–70 + N501Y + E gene triplexes (one opti...

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Detalles Bibliográficos
Autores principales: Pabbaraju, Kanti, Zelyas, Nathan, Wong, Anita, Croxen, Matthew A., Lynch, Tarah, Buss, Emily, Murphy, Stephanie, Shokoples, Sandy, Kanji, Jamil, Tipples, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134755/
https://www.ncbi.nlm.nih.gov/pubmed/35644262
http://dx.doi.org/10.1016/j.jviromet.2022.114553