Topological dynamics of an intrinsically disordered N‐terminal domain of the human androgen receptor

Human androgen receptor contains a large N‐terminal domain (AR‐NTD) that is highly dynamic and this poses a major challenge for experimental and computational analysis to decipher its conformation. Misfolding of the AR‐NTD is implicated in prostate cancer and Kennedy's disease, yet our knowledg...

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Detalles Bibliográficos
Autores principales: Sheikhhassani, Vahid, Scalvini, Barbara, Ng, Julian, Heling, Laurens W. H. J., Ayache, Yosri, Evers, Tom M. J., Estébanez‐Perpiñá, Eva, McEwan, Iain J., Mashaghi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Full‐length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134807/
https://www.ncbi.nlm.nih.gov/pubmed/35634773
http://dx.doi.org/10.1002/pro.4334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134807/
https://www.ncbi.nlm.nih.gov/pubmed/35634773
http://dx.doi.org/10.1002/pro.4334

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