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Male‐Specific Activation of Lysine Demethylases 5B and 5C Mediates Alcohol‐Induced Liver Injury and Hepatocyte Dedifferentiation

Alcohol‐associated liver disease (ALD) is a major cause of alcohol‐related mortality. Sex differences in sensitivity to ALD are well described, but these are often disregarded in studies of ALD development. We aimed to define sex‐specific pathways in liver exposed to alcohol. Mice were fed the Liebe...

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Detalles Bibliográficos
Autores principales: Schonfeld, Michael, Averilla, Janice, Gunewardena, Sumedha, Weinman, Steven A., Tikhanovich, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134811/
https://www.ncbi.nlm.nih.gov/pubmed/35084807
http://dx.doi.org/10.1002/hep4.1895