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HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle

Aims: Colorectal cancer (CRC) has high mortality and morbidity rates; however, the mechanism of CRC cells uncontrolled proliferation is unclarified, E3 ligases are widely reported to have crucial functions in cancers. HERC3 was once recognized as an important role in CRC, however its effects on CRC...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiyuan, Wu, Qi, Fang, Meimiao, Liu, Yu, Jiang, Ji, Feng, Qingyang, Hu, Ronggui, Xu, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134906/
https://www.ncbi.nlm.nih.gov/pubmed/35637966
http://dx.doi.org/10.7150/ijbs.72014