Single-cell transcriptomics reveals age-resistant maintenance of cell identities, stem cell compartments and differentiation trajectories in long-lived naked mole-rats skin

Naked mole-rats (NMR) are subterranean rodents characterized by an unusual longevity coupled with an unexplained resistance to aging. In the present study, we performed extensive in situ analysis and single-cell RNA-sequencing comparing young and older animals. At variance with other species, NMR ex...

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Detalles Bibliográficos
Autores principales: Savina, Aleksandra, Jaffredo, Thierry, Saldmann, Frederic, Faulkes, Chris G., Moguelet, Philippe, Leroy, Christine, Marmol, Delphine Del, Codogno, Patrice, Foucher, Lucy, Zalc, Antoine, Viltard, Mélanie, Friedlander, Gérard, Aractingi, Selim, Fontaine, Romain H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134947/
https://www.ncbi.nlm.nih.gov/pubmed/35507806
http://dx.doi.org/10.18632/aging.204054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134947/
https://www.ncbi.nlm.nih.gov/pubmed/35507806
http://dx.doi.org/10.18632/aging.204054

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