Progesterone receptor expression contributes to gemcitabine resistance at higher ECM stiffness in breast cancer cell lines

Chemoresistance poses a great barrier to breast cancer treatment and is thought to correlate with increased matrix stiffness. We developed two-dimensional (2D) polyacrylamide (PAA) and three-dimensional (3D) alginate in vitro models of tissue stiffness that mimic the stiffness of normal breast and b...

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Detalles Bibliográficos
Autores principales: Grant, Emma, Bucklain, Fatma A., Ginn, Lucy, Laity, Peter, Ciani, Barbara, Bryant, Helen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135204/
https://www.ncbi.nlm.nih.gov/pubmed/35617163
http://dx.doi.org/10.1371/journal.pone.0268300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135204/
https://www.ncbi.nlm.nih.gov/pubmed/35617163
http://dx.doi.org/10.1371/journal.pone.0268300

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