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Progesterone receptor expression contributes to gemcitabine resistance at higher ECM stiffness in breast cancer cell lines
Chemoresistance poses a great barrier to breast cancer treatment and is thought to correlate with increased matrix stiffness. We developed two-dimensional (2D) polyacrylamide (PAA) and three-dimensional (3D) alginate in vitro models of tissue stiffness that mimic the stiffness of normal breast and b...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135204/ https://www.ncbi.nlm.nih.gov/pubmed/35617163 http://dx.doi.org/10.1371/journal.pone.0268300 |