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Annotating functional effects of non-coding variants in neuropsychiatric cell types by deep transfer learning

Genomewide association studies (GWAS) have identified a large number of loci associated with neuropsychiatric traits, however, understanding the molecular mechanisms underlying these loci remains difficult. To help prioritize causal variants and interpret their functions, computational methods have...

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Detalles Bibliográficos
Autores principales: Lai, Boqiao, Qian, Sheng, Zhang, Hanwei, Zhang, Siwei, Kozlova, Alena, Duan, Jubao, Xu, Jinbo, He, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135341/
https://www.ncbi.nlm.nih.gov/pubmed/35576194
http://dx.doi.org/10.1371/journal.pcbi.1010011