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Correlations from structure and phylogeny combine constructively in the inference of protein partners from sequences
Inferring protein-protein interactions from sequences is an important task in computational biology. Recent methods based on Direct Coupling Analysis (DCA) or Mutual Information (MI) allow to find interaction partners among paralogs of two protein families. Does successful inference mainly rely on c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135348/ https://www.ncbi.nlm.nih.gov/pubmed/35576238 http://dx.doi.org/10.1371/journal.pcbi.1010147 |