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Correlations from structure and phylogeny combine constructively in the inference of protein partners from sequences

Inferring protein-protein interactions from sequences is an important task in computational biology. Recent methods based on Direct Coupling Analysis (DCA) or Mutual Information (MI) allow to find interaction partners among paralogs of two protein families. Does successful inference mainly rely on c...

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Detalles Bibliográficos
Autores principales: Gerardos, Andonis, Dietler, Nicola, Bitbol, Anne-Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135348/
https://www.ncbi.nlm.nih.gov/pubmed/35576238
http://dx.doi.org/10.1371/journal.pcbi.1010147

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