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Regulation of protein complex partners as a compensatory mechanism in aneuploid tumors

Aneuploidy, a state of chromosome imbalance, is a hallmark of human tumors, but its role in cancer still remains to be fully elucidated. To understand the consequences of whole-chromosome-level aneuploidies on the proteome, we integrated aneuploidy, transcriptomic, and proteomic data from hundreds o...

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Detalles Bibliográficos
Autores principales: Senger, Gökçe, Santaguida, Stefano, Schaefer, Martin H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135399/
https://www.ncbi.nlm.nih.gov/pubmed/35575458
http://dx.doi.org/10.7554/eLife.75526