Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration

De novo limb regeneration after amputation is restricted in mammals to the distal digit tip. Central to this regenerative process is the blastema, a heterogeneous population of lineage-restricted, dedifferentiated cells that ultimately orchestrates regeneration of the amputated bone and surrounding...

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Detalles Bibliográficos
Autores principales: Tower, Robert J, Busse, Emily, Jaramillo, Josue, Lacey, Michelle, Hoffseth, Kevin, Guntur, Anyonya R, Simkin, Jennifer, Sammarco, Mimi C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135401/
https://www.ncbi.nlm.nih.gov/pubmed/35616636
http://dx.doi.org/10.7554/eLife.71542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135401/
https://www.ncbi.nlm.nih.gov/pubmed/35616636
http://dx.doi.org/10.7554/eLife.71542

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