Optimization of mirtazapine loaded into mesoporous silica nanostructures via Box-Behnken design: in-vitro characterization and in-vivo assessment

Employment of mesoporous silica nanostructures (MSNs) in the drug delivery field has shown a significant potential for improving the oral delivery of active pharmaceutical products with low solubility in water. Mirtazapine (MRT) is a tetracyclic antidepressant with poor water solubility (BCS Class I...

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Detalles Bibliográficos
Autores principales: Musallam, Abeer A., Mahdy, M. A., Elnahas, Hanan M., Aldeeb, Reem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135429/
https://www.ncbi.nlm.nih.gov/pubmed/35612286
http://dx.doi.org/10.1080/10717544.2022.2075985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135429/
https://www.ncbi.nlm.nih.gov/pubmed/35612286
http://dx.doi.org/10.1080/10717544.2022.2075985

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