Models of enzyme inhibition and apparent dissociation constants from kinetic analysis to study the differential inhibition of aldose reductase

In order to explain the negative slope of [Image: see text] versus inhibitor concentration observed in the study of epigallocatechin gallate acting as an inhibitor of aldose reductase, a kinetic analysis was performed to rationalise the phenomenon. Classical and non-classical models of complete and...

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Detalles Bibliográficos
Autores principales: Balestri, Francesco, Cappiello, Mario, Moschini, Roberta, Mura, Umberto, Del-Corso, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135441/
https://www.ncbi.nlm.nih.gov/pubmed/35607924
http://dx.doi.org/10.1080/14756366.2022.2076089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135441/
https://www.ncbi.nlm.nih.gov/pubmed/35607924
http://dx.doi.org/10.1080/14756366.2022.2076089

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