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Models of enzyme inhibition and apparent dissociation constants from kinetic analysis to study the differential inhibition of aldose reductase
In order to explain the negative slope of [Image: see text] versus inhibitor concentration observed in the study of epigallocatechin gallate acting as an inhibitor of aldose reductase, a kinetic analysis was performed to rationalise the phenomenon. Classical and non-classical models of complete and...
Autores principales: | Balestri, Francesco, Cappiello, Mario, Moschini, Roberta, Mura, Umberto, Del-Corso, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135441/ https://www.ncbi.nlm.nih.gov/pubmed/35607924 http://dx.doi.org/10.1080/14756366.2022.2076089 |
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