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Validation of ketamine as a pharmacological model of thalamic dysconnectivity across the illness course of schizophrenia

N-methyl-D-aspartate receptor (NMDAR) hypofunction is a leading pathophysiological model of schizophrenia. Resting-state functional magnetic resonance imaging (rsfMRI) studies demonstrate a thalamic dysconnectivity pattern in schizophrenia involving excessive connectivity with sensory regions and de...

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Detalles Bibliográficos
Autores principales: Abram, Samantha V., Roach, Brian J., Fryer, Susanna L., Calhoun, Vince D., Preda, Adrian, van Erp, Theo G. M., Bustillo, Juan R., Lim, Kelvin O., Loewy, Rachel L., Stuart, Barbara K., Krystal, John H., Ford, Judith M., Mathalon, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135621/
https://www.ncbi.nlm.nih.gov/pubmed/35422467
http://dx.doi.org/10.1038/s41380-022-01502-0