Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear

N-methyl-D-aspartate receptor (NMDAR) modulators have recently received increased attention as potential therapeutics for posttraumatic stress disorder (PTSD). Here, we tested a novel NMDAR-positive modulator, NYX-783, in the following two rodent models of PTSD: an auditory fear-conditioning model a...

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Detalles Bibliográficos
Autores principales: Lee, Boyoung, Pothula, Santosh, Wu, Min, Kang, Hyeyeon, Girgenti, Matthew J., Picciotto, Marina R., DiLeone, Ralph J., Taylor, Jane R., Duman, Ronald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135632/
https://www.ncbi.nlm.nih.gov/pubmed/35418600
http://dx.doi.org/10.1038/s41380-022-01498-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135632/
https://www.ncbi.nlm.nih.gov/pubmed/35418600
http://dx.doi.org/10.1038/s41380-022-01498-7

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