Encapsulation of MERS antigen into α-GalCer-bearing-liposomes elicits stronger effector and memory immune responses in immunocompetent and leukopenic mice

OBJECTIVES: Here, we prepared a liposome-based vaccine formulation containing Middle East Respiratory Syndrome Coronavirus papain-like protease (MERS-CoV-PLpro). METHODS: A persistent leukopenic condition was induced in mice by injecting cyclophosphamide (CYP) three days before each dose of immuniza...

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Detalles Bibliográficos
Autores principales: Khan, Masood Alam, Khan, Arif, Alzohairy, Mohammad A., Alruwetei, Abdulmohsen M., Alsahli, Mohammed A., Allemailem, Khaled S., Alrumaihi, Faris, Almatroudi, Ahmad, Alhatlani, Bader Y., Rugaie, Osamah Al, Malik, Ajamaluddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. on behalf of King Saud University. 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135648/
https://www.ncbi.nlm.nih.gov/pubmed/35663348
http://dx.doi.org/10.1016/j.jksus.2022.102124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135648/
https://www.ncbi.nlm.nih.gov/pubmed/35663348
http://dx.doi.org/10.1016/j.jksus.2022.102124

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