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Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles

Sequence homology between SARS-CoV-2 and common-cold human coronaviruses (HCoVs) raises the possibility that memory responses to prior HCoV infection can affect T cell response in COVID-19. We studied T cell responses to SARS-CoV-2 and HCoVs in convalescent COVID-19 donors and identified a highly co...

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Detalles Bibliográficos
Autores principales: Becerra-Artiles, Aniuska, Calvo-Calle, J. Mauricio, Co, Mary Dawn, Nanaware, Padma P., Cruz, John, Weaver, Grant C., Lu, Liying, Forconi, Catherine, Finberg, Robert W., Moormann, Ann M., Stern, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135679/
https://www.ncbi.nlm.nih.gov/pubmed/35675811
http://dx.doi.org/10.1016/j.celrep.2022.110952