Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis

Mammalian spermatogenesis is a heat-vulnerable process that occurs at low temperatures, and elevated testicular temperatures cause male infertility. However, the current reliance on in vivo assays limits their potential to detail temperature dependence and destructive processes. Using ex vivo cultur...

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Detalles Bibliográficos
Autores principales: Hirano, Kodai, Nonami, Yuta, Nakamura, Yoshiaki, Sato, Toshiyuki, Sato, Takuya, Ishiguro, Kei-ichiro, Ogawa, Takehiko, Yoshida, Shosei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135715/
https://www.ncbi.nlm.nih.gov/pubmed/35618762
http://dx.doi.org/10.1038/s42003-022-03449-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135715/
https://www.ncbi.nlm.nih.gov/pubmed/35618762
http://dx.doi.org/10.1038/s42003-022-03449-y

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